Lehne: Pharmacology for Nursing Care, 7th Edition

Chapter 01: Orientation to Pharmacology

Test Bank

MULTIPLE CHOICE

	1.	The student is providing a presentation to the class regarding concepts in pharmacodynamics. Which statement made by a student in the class best demonstrates understanding of pharmacodynamics?
a.	“Excretion and metabolism are components of pharmacodynamics.”	
b.	“Receptor binding is the main component of pharmacodynamics.”	
c.	“Age and gender are components of pharmacodynamics.”	
d.	“Routes of administration are components of pharmacodynamics.”	

ANS:	B
Receptor binding is the main component of pharmacodynamics. Excretion and metabolism are components of pharmacokinetics. Age and gender are biologic/physiologic variations. Routes of administration are considered pharmacokinetics.

PTS:	1	DIF:	Cognitive Level: Comprehension	REF:	p. 3
TOP:	Nursing Process: Evaluation	
MSC:	NCLEX Client Needs Category: Physiological Integrity: Pharmacological and Parenteral Therapies		

	2.	The nurse is administering morning medications. A patient questions the nurse, “How does the drug know where to go?” The nurse’s best response to the patient is based on the understanding that a drug that elicits only those responses for which it is given is considered
a.	safe.	c.	selective.	
b.	effective.	d.	predictable.	

ANS:	C
Selectivity defines a drug that elicits only those responses for which it is given. There are no drugs that are considered safe by definition. “Effective” is a term that describes a drug that is doing what it is expected to do. A predictable drug response will have the mechanism of action that is expected from it.

PTS:	1	DIF:	Cognitive Level: Comprehension	REF:	p. 2
TOP:	Nursing Process: Diagnosis	
MSC:	NCLEX Client Needs Category: Physiological Integrity: Pharmacological and Parenteral Therapies		

	3.	A nurse is teaching a continuing education class on pharmacology. The nurse is evaluating the participants’ knowledge and poses the question, “When a disease process triggers increased metabolism of the drug, the disease has altered the drug’s ___________.”
a.	pharmacodynamics	c.	pharmacotherapeutics	
b.	pharmacokinetics	d.	selectivity	

ANS:	B
Metabolism is a component of pharmacokinetics. Pharmacodynamics is the impact of drugs on the body. Pharmacotherapeutics refers to the use of drugs to diagnose, prevent, or treat disease or to prevent pregnancy. Selectivity refers to the ability of a drug to elicit only the response for which it is given.

PTS:	1	DIF:	Cognitive Level: Comprehension	REF:	pp. 2-3
TOP:	Nursing Process: Evaluation	
MSC:	NCLEX Client Needs Category: Physiological Integrity: Physiological Adaptation

	4.	A patient with type I diabetes mellitus comes to the clinic with complaints of low blood sugar. The nurse questions the patient regarding compliance with medications. The patient states that she gives herself more insulin per dose so she doesn’t have to take it as often. Which factors should the nurse educate the patient about as affecting the patient’s response to the medication?
a.	Administration	c.	Pharmacodynamics	
b.	Pharmacokinetics	d.	Chemical stability	

ANS:	A
Administration of medications relates to the appropriate dosage amount, route, and timing of administration and is an important determinant of a patient’s drug response. Pharmacokinetics determines how much of an administered dose gets to its sites of action. Pharmacodynamics is the impact of drugs on the body; it determines the nature of the response and is not directly related to dose and compliance. Chemical stability relates to the stability of the medication when mixed in solution or with another form or preparation or when stored on a shelf.

PTS:	1	DIF:	Cognitive Level: Analysis	REF:	pp. 2-3
TOP:	Nursing Process: Implementation	
MSC:	NCLEX Client Needs Category: Physiological Integrity: Pharmacological and Parenteral Therapies		

MULTIPLE RESPONSE

	1.	What are the properties of an ideal drug? (Select all that apply.)
a.	Irreversible action	
b.	Predictability	
c.	Ease of administration	
d.	Chemical stability	
e.	A simple trade name	

ANS:	B, C, D
In addition to predictability, ease of administration, and chemical stability, other properties would include a reversible action to undo any harm the drug may have caused and a simple generic name, because generic names are usually complex and difficult to remember and pronounce.

PTS:	1	DIF:	Cognitive Level: Comprehension	REF:	p. 2
TOP:	Nursing Process: Assessment	
MSC:	NCLEX Client Needs Category: Physiological Integrity: Pharmacological and Parenteral Therapies